منابع مشابه
Antigens in Immunity
Flagellar antigens from S. adelaide bacteria were labelled with carrier-free (125)I so as to achieve a substitution rate of 0.1 to 2.1 radioactive iodine atoms per flagellin molecule. Lymph nodes from rats injected with small amounts of these antigens were teased into a single cell suspension. Single antibody-forming cells were identified and submitted individually to autoradiography so as to m...
متن کاملTough antigens trigger immunity
Signaling between a T cell and an antigen-presenting cell (APC) is orchestrated through a bull's eye–like structure known as the immunological synapse. But no one had ever spotted these structures in vivo, causing many to wonder whether they are immunology's equivalent of the Loch Ness monster. Synapse devotees can now rest easy, thanks to Barcia et al., who provide the first in vivo glimpse of...
متن کاملBALB/c Mice Immunity to Hydatidosis Induced by In-vitro Reared Echinococcus granulosus Adult Worm Antigens
Background: Echinococcosis is a zoonotic parasitic disease caused by the larval stage of Echinococcus granulosus. Several native and recombinant antigens, derived from different stages of E. granulosus life cycle, have been used for vaccine trials. In vitro reared adult worms are good candidates for vaccination as they do not produce fertile egg/s and do not have any risk of contamination for r...
متن کاملContrasuppression, class I antigens, and cancer immunity.
When immunologic homeostasis is perturbed by antigen, the failure to accomodate that antigen as "self" usually results in what we observe as an immune response. In the case of tumors, however, a massive bombardment of the system with tumor antigens can induce a potent general suppression of immunity such that the tumor must often be removed before immunity can be demonstrated [I]. Such observat...
متن کامل(viral transformation/viral-coded antigens/tumor immunity)
Feline sarcoma virus (FeSV) rescued from transformed nonproducer mink or rat cells contains two FeSV-specific antigens (p15 and p12), and the feline oncornavirus-associated cell membrane antigen (FOCMA). All three antigens are helper virus-independent and are encoded by the FeSV genome. FOCMA, pl5, and p12 antigens cochromatograph as phosphorylated molecules of 85,000 molecular weight (pp85), a...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1964
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.120.6.1075